发明名称 IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS
摘要 There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.
申请公布号 US2012083492(A1) 申请公布日期 2012.04.05
申请号 US201013264544 申请日期 2010.04.16
申请人 PASTOR FERNANDEZ JOAQUIN;MARTINEZ GONZALEZ SONIA;OYARZABAL SANTAMARINA JULEN;CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO) 发明人 PASTOR FERNANDEZ JOAQUIN;MARTINEZ GONZALEZ SONIA;OYARZABAL SANTAMARINA JULEN
分类号 A61K31/5377;A61K31/4985;A61P1/16;A61P3/00;A61P3/10;A61P5/00;A61P9/00;A61P9/10;A61P11/00;A61P17/06;A61P19/02;A61P19/08;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P31/12;A61P31/14;A61P35/00;A61P35/02;A61P37/00;A61P37/06;A61P37/08;A61P41/00;C07D487/04 主分类号 A61K31/5377
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