发明名称 PREPARATION FOR IMPROVING SOLUBILITY OF POORLY SOLUBLE DRUG
摘要 Provided is a solubility-improving preparation for improving the oral absorbability of a poorly soluble drug, which is characterized by comprising: (A) granules each of which contains 1) a poorly soluble drug having an acidic group in the molecule, 2) an alkaline agent and 3) a surfactant and which contains substantially no disintegrating agent; and (B) a disintegrating agent which is present only in the outside of the granules.
申请公布号 CA2813147(A1) 申请公布日期 2012.04.05
申请号 CA20112813147 申请日期 2011.09.29
申请人 SHIONOGI & CO., LTD. 发明人 SAKUMA, SATOSHI;UEDA, HIROSHI;MASHIMO, AKIRA;MURAZATO, HIROSHI
分类号 A61K31/426;A61K9/20;A61K9/48;A61K31/405;A61K47/02;A61K47/20;A61K47/36;A61K47/38 主分类号 A61K31/426
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