发明名称 |
PREPARATION FOR IMPROVING SOLUBILITY OF POORLY SOLUBLE DRUG |
摘要 |
Provided is a solubility-improving preparation for improving the oral absorbability of a poorly soluble drug, which is characterized by comprising: (A) granules each of which contains 1) a poorly soluble drug having an acidic group in the molecule, 2) an alkaline agent and 3) a surfactant and which contains substantially no disintegrating agent; and (B) a disintegrating agent which is present only in the outside of the granules. |
申请公布号 |
CA2813147(A1) |
申请公布日期 |
2012.04.05 |
申请号 |
CA20112813147 |
申请日期 |
2011.09.29 |
申请人 |
SHIONOGI & CO., LTD. |
发明人 |
SAKUMA, SATOSHI;UEDA, HIROSHI;MASHIMO, AKIRA;MURAZATO, HIROSHI |
分类号 |
A61K31/426;A61K9/20;A61K9/48;A61K31/405;A61K47/02;A61K47/20;A61K47/36;A61K47/38 |
主分类号 |
A61K31/426 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|