| 发明名称 |
6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonists |
| 摘要 |
The present invention provides 6-substituted-2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula (I) as selective 5-HT receptor agonists for the treatment of 5-HT associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: where R is -C≡C-R, -CH=CRR , or -(C-C)alkyl-Ar optionally substituted on the alkyl moiety with 1 to 6 fluoro substituents and other substituents are as defined in the specification. |
| 申请公布号 |
AU2006287160(B2) |
申请公布日期 |
2012.04.05 |
| 申请号 |
AU20060287160 |
申请日期 |
2006.09.01 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
MARTINEZ-GRAU, MARIA ANGELES;HOYING, RICHARD CHARLES;BRINER, KARIN;CAMP, ANNE MARIE;SAPMAZ, SELMA;ALLEN, JOHN GORDON;CASES-THOMAS, MANUEL JAVIER;RATHMELL, RICHARD EDMUND;WILLIAMS, ANDREW CAERWYN;MAZANETZ, MICHAEL PHILIP;ROTHHAAR, ROGER RYAN;POKROVSKAIA, NATALIA |
| 分类号 |
C07D223/16;A61K31/55;A61P3/04;A61P25/00;A61P25/22;A61P25/24;C07D401/06;C07D403/04;C07D409/04;C07D417/06 |
主分类号 |
C07D223/16 |
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