| 发明名称 |
COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES |
| 摘要 |
Compounds useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.
|
| 申请公布号 |
US2012083495(A1) |
申请公布日期 |
2012.04.05 |
| 申请号 |
US201113310965 |
申请日期 |
2011.12.05 |
| 申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY,;SCIENCE APPLICATIONS INTERNATIONAL INC. (SAIC);ALBANY MOLECULAR RESEARCH, INC.;DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
HEEMSKERK JILL;BARNES KEITH D.;MCCALL JOHN M.;JOHNSON GRAHAM;FAIRFAX DAVID;JOHNSON MATTHEW ROBERT |
| 分类号 |
A61K31/5377;A61K31/403;A61K31/4035;A61K31/4439;A61K31/454;A61K31/506;A61P3/10;A61P21/00;A61P25/00;A61P25/08;A61P25/16;A61P25/28;A61P31/12;A61P35/00;C07D209/46;C07D401/10;C07D403/10;C07D405/10;C07D409/10;C07D413/10;C12N5/071 |
主分类号 |
A61K31/5377 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
