| 发明名称 |
Peptides binding to phosphatidylethanolamine and their use in treating viral infections and cancer |
| 摘要 |
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and 5 compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases. 459460_1 (GHMatters) 1/10/09 |
| 申请公布号 |
AU2009222538(B2) |
申请公布日期 |
2012.04.05 |
| 申请号 |
AU20090222538 |
申请日期 |
2009.10.01 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
SOARES, MELINA M.;HE, JIN;THORPE, PHILIP E. |
| 分类号 |
A61K45/00;C07K16/28;A61K39/395;A61P3/04;A61P3/10;A61P5/14;A61P7/04;A61P7/06;A61P9/10;A61P15/08;A61P17/00;A61P17/10;A61P19/02;A61P19/06;A61P27/02;A61P27/06;A61P29/00;A61P31/10;A61P31/12;A61P31/22;A61P33/00;A61P35/00;A61P37/02;A61P43/00;C07K16/18;C07K16/44 |
主分类号 |
A61K45/00 |
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