发明名称 |
PROCESSES FOR THE PREPARATION OF GLUTAMIC ACID COMPOUNDS AND INTERMEDIATES THEREOF AND NOVEL INTERMEDIATES USED IN THE PROCESSES |
摘要 |
A process for preparing industrially and efficiently glutamic acid compounds (such as monatin) useful as sweeteners or intermediates for the production of drugs or the like: a process for preparation of intermediates used therein: novel intermediates included among them: a process for preparation of optically active monatin: a process for preparation of intermediates used therein: and novel intermediates included among them. Specifically, a process for the preparation of glutamic acid compounds (or salts thereof) including monatin, which comprises preparing a ketoglutaric acid compound serving as a precursor of the objective glutamic acid compound by condensing a specific pyruvic acid compound with oxalacetic acid or pyruvic acid through cross-aldol reaction and, if necessary, subjecting the obtained condensate to decarboxylation, and replacing the carbonyl group of the ketoglutaric acid compound by an amino group. |
申请公布号 |
EP1466890(B1) |
申请公布日期 |
2012.04.04 |
申请号 |
EP20020783682 |
申请日期 |
2002.11.29 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
KAWAHARA, SHIGERU;AMINO, YUSUKE;MORI, KENICHI;FUNAKOSHI, NAO;TAKEMOTO, TADASHI |
分类号 |
C07D209/20;A23G3/00;A23L2/60;A23L27/10;A23L27/20;A23L27/30;C07C51/353;C07C51/38;C07C59/285;C07C59/347;C07C59/48;C07C227/08;C07C229/00;C07C229/24;C07C229/36;C07C251/36;C07D209/08;C07D403/06;C07D405/06 |
主分类号 |
C07D209/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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