发明名称 FORMULATION OF FINE PARTICLES USING LIQUEFIED OR DENSE GASES
摘要 <p>The invention provides a method for manipulating or formulating a solid substance which melts under pressure of a gas without degrading at a temperature lower than the melting point of the substance at atmospheric pressure including: applying to the substance a liquefied gas or dense gas to melt the substance without degrading the substance; then contacting the molten substance with a carrier fluid, which is at substantially the same pressure as the liquefied gas or dense gas, to form a solution or mixture of at least a part of the molten substance and the carrier fluid; and passing the solution or mixture into a vessel of lower pressure than the pressure of the liquefied gas or dense gas and carrier fluid to form particles of the substance; and particles formed by the method.</p>
申请公布号 EP1499296(B1) 申请公布日期 2012.04.04
申请号 EP20030746782 申请日期 2003.04.15
申请人 MAP PHARMACEUTICALS INC 发明人 FOSTER, NEIL RUSSELL;REGTOP, HUBERT LEONARDUS;DEHGHANI, FARIBA;TANDYA, ANDRIAN
分类号 A61K9/14;A61K9/00;A61K9/51;A61K31/192;A61K38/13;B01J2/02 主分类号 A61K9/14
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