发明名称 |
Method and an apparatus for determining nucleotide sequence, and a computer program product to be executed by the apparatus |
摘要 |
A method for determining nucleotide sequence encompasses: injecting a solution containing a sample DNA into a chip cartridge provided with a detecting electrode, to which a probe DNA is immobilized; introducing an intercalator solution in the chip cartridge; obtaining a current-voltage characteristic curve by measuring a current in the solution due to an electrochemical reaction of the intercalator through the detecting electrode; obtaining a baseline by linearly approximating the current-voltage characteristic curve; obtaining a net current value by subtracting, from a peak current value of the current-voltage characteristic curve, a baseline current value obtained from the baseline at a peak voltage value defining the peak current value; and identifying a nucleotide sequence in the sample DNA, using the net current value. |
申请公布号 |
US8150635(B2) |
申请公布日期 |
2012.04.03 |
申请号 |
US20100949411 |
申请日期 |
2010.11.18 |
申请人 |
HONGO SADATO;YANAGA SHINJI;KABUSHIKI KAISHA TOSHIBA |
发明人 |
HONGO SADATO;YANAGA SHINJI |
分类号 |
G06F19/00;C12Q1/68;G01N27/26;G01N27/327;G01N27/416;G01N27/48;G01N31/00;G01N33/48;G06F19/20 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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