发明名称 |
Heteroaromatic glucokinase activators |
摘要 |
The present invention describes 2,3-di-substituted N-heteroaromatic propionamides, of Formula (I) wherein the substitution at the 3-position is an optionally substituted phenyl ring and the substitution at the 2-position is an alkyl or cycloalkyl group; pharmaceutical compositions comprising the same; and, methods of using the same. The propionamides are glucokinase activators for the treatment of type II diabetes. |
申请公布号 |
US8148412(B2) |
申请公布日期 |
2012.04.03 |
申请号 |
US20050791200 |
申请日期 |
2005.12.05 |
申请人 |
JEPPESEN LONE;KRISTIANSEN MARIT;NOVO NORDISK A/S |
发明人 |
JEPPESEN LONE;KRISTIANSEN MARIT |
分类号 |
A61K31/426;C07D275/03;C07D277/46 |
主分类号 |
A61K31/426 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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