| 摘要 |
<p>Disclosed are benzimidazole and triazolopyridazinesulfanyl bezothiazole compounds represented by general formula (I). Examples of the compounds of formula (I) include methyl(6-{ [6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulphanyl} -1,3-banzothiazol-2-amine and 1-[2-(diethylamino)ethyl]-3-(6-{ [6-(4-fluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulphanyl} -1,3-benzothiazol-2-yl)urea. Also disclosed is the use of the compounds of formula (I) for treating blood vessel proliferation disorders, fibrotic disorders, `mesangial' cell proliferation disorders, metabolic disorders, allergies, asthma, thrombosis, nervous system diseases, retinopathy, psoriasis, rheumatoid arthritis, diabetes, muscle degeneration and cancers.</p> |
