COMPOSITIONS FOR DEGRADING CELLULOSIC MATERIAL

摘要

Provided is an isolated filamentous fungal host cell, comprising: (a) a first polynucleotide encoding a native or heterologous GH61 polypeptide having cellulolytic enhancing activity; (b) a second polynucleotide encoding a native or heterologous beta-glucosidase; and (c) one or more third polynucleotides encoding native or heterologous cellulolytic enzymes selected from the group consisting of a Trichoderma reesei cellobiohydrolase I (CEL7A), a Trichoderma reesei cellobiohydrolase II (CEL6A), and a Trichoderma reesei endoglucanase I (CEL7B), and orthologs or functional variants thereof, all with specified protein coding sequences. The cells can be used to process cellulose containing substrates by fermentation.