PYRIDAZINONE DERIVATIVES AS H3 INHIBITORS

摘要

Disclosed herein are pyridizinone derivatives of formula I* wherein R2 is located para to the Y-(CHR4)mR1 group and the substituents are as defined within the spec, processes for their preparation, compositions comprising said compounds. Said compounds are useful in the treatment of a disorder such as narcolepsy or sleep/wake disorders, feeding behaviour, eating disorders, obesity, cognition, arousal, memory, mood disorders, mood attention alteration, attention deficit hyperactivity disorder (ADHD), Alzheimer's disease/dementia, schizophrenia, pain, stress, migraine, motion sickness, depression, psychiatric disorders, epilepsy, gastrointestinal disorders, respiratory disorders, inflammation and myocardial infarction.