METHOD FOR THE SYNTHESIS OF N- [3- [ (2-METHOXYPHENYL) SULFANYL] -2- METHYLPROPYL] -3,4-DIHYDRO-2H-1,5-BENZOXATHIEPIN-3-AMINE<0

摘要

Disclosed is a process for the preparation of N-[3-[(2-methoxyphenyl)sulfanyl]-2-methylpropyl]-3,4-dihydro-2H-1,5-benzoxathiepin-3-amine of general formula (1) which uses condensation of the intermediates of 3, 4-dihydro-2H-1,5-benzoxathiepine (2) and methoxyphenylsulfonyl)-2-methylpropane sulphonate (3) wherein the radical R is a methyl group or a 4-methylphenyl group.