3-SUBSTITUTED-[1,2,3]BENZOTRIAZINONE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES

摘要

Disclosed is a compound according to the formula(I) e.g. 3-[2-(3-Fluorophenyl)ethyl] 6a,7,8,9-tetrahydro-3H-pyrrolo[2',1':2,3][1,3]oxazino[6,5-g][1,2,3]benzotriazine-4,11-dione Wherein the substituents are defined in the specification or a pharmaceutically acceptable addition salt of an acid or base thereof for use in the treatment of Parkinson's disease, Attention Deficit Hyperactivity Disorder, Rett Syndrome, Fragile-X Syndrome, Respiratory Depression, Cognitive Disorders and Alzheimer's disease.