| 摘要 |
Disclosed are dihydrobenzo-dioxin compounds represented by general formula (I), or pharmaceutically acceptable salts or esters thereof. Examples of the compounds of formula (I) include 1-(2,3-dihydrobenzo[ 1,4 ]dioxin-2-ylmethyl)-5-phenyl-l ,2,3 ,6-tetrahydropyridine, 1-(2,3-dihydrobenzo[ 1,4 ]dioxin-2-ylmethyl)-3-phenylpiperidine and 1-(2,3-dihydrobenzo[I,4 ]dioxin-2-ylmethyl)-3-(2-methoxyphenyl)piperidine, 3-( 4-chlorophenyl)-I-(2,3-dihydrobenzo[ 1,4 ] dioxin-2-ulmethyl)piperidine, The compounds of formula (I) are useful in treating a mental disorder propagated by stress, Parkinson's disease, depression, schizophrenia, attention deficit hyperactivity disorder, post-traumatic stress disorder, obsessive compulsive disorder, Tourette's syndrome, blepharospasm or other focal dystonias, temporal lobe epilepsy with psychosis, a drug-induced psychosis, Huntington's disease, a disorder caused by fluctuation of the levels of sex hormones, panic disorder, Alzheimer's disease or mild cognitive impairment.
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