C2-C5-ALKYL-IMIDAZOLE-BISPHOSPHONATES

摘要

Disclosed is a compound of formula (I) wherein one of R1 and R2 is hydrogen and the other is C2-C5-alkyl that can be branched or unbranched, or an ester, and/or a salt thereof. The compounds are formed through the reaction of an imidazolyl carboxylic acid precursor with a phosphorus oxyhalogenide to give a compound of formula I or a salt thereof. The compounds can be used as a pharmaceutical for treating excessive or inappropriate bone resorption or a disease caused by excessive prenylation of target proteins.