BIONIC AORTIC BAROREFLEX SYSTEM FOR TREATING DISEASE ASSOCIATED WITH AORTIC BAROREFLEX DYSFUNCTION

摘要

The present invention provides a bionic aortic baroreflex system which restores normal volume tolerance in the absence of physiological aortic baroreflex and, therefore, is useful in treating HFpEF. More specifically, the invention provides a bionic aortic baroreflex system comprising: an aortic pressure sensing means (aortic pressure (AP) sensor) for sensing aortic pressure data from a living organism and outputting an aortic pressure signal; a calculation means (regulator) for inputting the aortic pressure signal, which is sensed by the aortic pressure sensing means, calculating a clinically effective aortic depressor nerve stimulation signal and outputting the aortic depressor nerve stimulation signal; and an aortic depressor nerve stimulation means (electrical nerve stimulator) for inputting the aortic depressor nerve stimulation signal, which is calculated by the calculation means, and stimulating the aortic depressor nerve of the living organism on the basis of the aortic depressor nerve stimulation signal.