发明名称 |
METHOD FOR PRODUCING 2-BORONATED AZULENE DERIVATIVE |
摘要 |
The purpose of the invention is to provide a method for obtaining a boron-containing group, particularly a substituent derived from a borate ester or the like at the 2-position in high yield in a relatively short time using azulene or an azulene derivative as a starting material. In particular, the invention addresses the problem of obtaining an azulenylating agent suitable for introducing a guaiazulene group, which is useful for pharmaceuticals and the like. The invention is characterized in that when azulene or an azulene derivative is reacted with a boronating agent in the presence of a catalyst comprising an organic complex with a platinum group metal, phenanthroline or a derivative thereof is allowed to coexist. |
申请公布号 |
WO2012039135(A1) |
申请公布日期 |
2012.03.29 |
申请号 |
WO2011JP05315 |
申请日期 |
2011.09.21 |
申请人 |
YAMAGUCHI UNIVERSITY;FUJINAGA, MASAYUKI;MURAFUJI, TOSHIHIRO;HIYAMA, KUMIKO |
发明人 |
FUJINAGA, MASAYUKI;MURAFUJI, TOSHIHIRO;HIYAMA, KUMIKO |
分类号 |
C07F5/02;C07B61/00;C07F5/04 |
主分类号 |
C07F5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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