<p>Disclosed are 4-amino-2-butenamides of Formula (I) having pharmacological activity, pharmaceutical compositions containing them, and methods for the treatment of diseases mediated by the cathepsin C enzyme such as chronic obstructive pulmonary disease.</p>
申请公布号
SG178232(A1)
申请公布日期
2012.03.29
申请号
SG20120007472
申请日期
2010.08.11
申请人
GLAXO GROUP LIMITED
发明人
ANDERSON, NIALL;BUSCH-PETERSEN, JAKOB;EVANS, BRIAN;LI, HUIJIE;NEVINS, NEYSA;PALOVICH, MICHAEL, R.;SOLLIS, STEVEN, L.;WALL, MICHAEL, D.;BULLION, ANN M.