发明名称 ANTISENSE MODULATION OF C-REACTIVE PROTEIN EXPRESSION
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of C-reactive protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding C-reactive protein. Methods of using these compounds for modulation of C-reactive protein expression and for treatment of diseases associated with expression of C-reactive protein are provided.
申请公布号 US2012077866(A1) 申请公布日期 2012.03.29
申请号 US201113309835 申请日期 2011.12.02
申请人 CROOKE ROSANNE M.;GRAHAM MARK J.;ISIS PHARMACEUTICALS, INC. 发明人 CROOKE ROSANNE M.;GRAHAM MARK J.
分类号 A61K31/7088;C12N15/09;A61K38/00;A61K48/00;A61P3/04;A61P9/00;A61P9/10;A61P13/12;A61P17/02;A61P19/02;A61P29/00;A61P31/00;A61P35/00;C07H21/00;C12N5/07;C12N15/113 主分类号 A61K31/7088
代理机构 代理人
主权项
地址