发明名称 |
ATROPISOMERS OF PI3K-INHIBITING COMPOUNDS |
摘要 |
The invention provides compounds, compositions and methods to treat certain inflammatory conditions or cancers by administering a compound that inhibits PI3K isoforms, wherein the compounds are optically active atropisomers. It provides optically active stereoisomers of a class of pyrazole-containing compounds, which are useful for these methods, and provides methods to obtain these compounds as well as pharmaceutical compositions containing these compounds. |
申请公布号 |
WO2012040634(A1) |
申请公布日期 |
2012.03.29 |
申请号 |
WO2011US53102 |
申请日期 |
2011.09.23 |
申请人 |
GILEAD CALISTOGA LLC;EVARTS, JERRY, B.;ULRICH, ROGER, G. |
发明人 |
EVARTS, JERRY, B.;ULRICH, ROGER, G. |
分类号 |
C07D487/04;A61K31/4985;A61P29/00 |
主分类号 |
C07D487/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|