发明名称 |
2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT |
摘要 |
Provided are select imidazo[1,2-f][1,2,4] triazinyl nucleosides, nucleoside phosphates and prodrugs thereof, wherein the 2' position of the nucleoside sugar is substituted with halogen and carbon substituents. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections caused by both wild type and mutant strains of HCV. Formula (I) |
申请公布号 |
WO2012039791(A1) |
申请公布日期 |
2012.03.29 |
申请号 |
WO2011US29441 |
申请日期 |
2011.03.22 |
申请人 |
GILEAD SCIENCES, INC.;CHO, AESOP;KIM, CHOUNG;RAY, ADRIAN |
发明人 |
CHO, AESOP;KIM, CHOUNG;RAY, ADRIAN |
分类号 |
C07D487/04;A61K31/41 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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