<p>The present invention relates to the provision of novel immunogens comprising an antigenic PCSK9 peptide linked to an immunogenic carrier for the prevention, treatment or alleviation of PCSK9-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.</p>
申请公布号
AU2010290931(A1)
申请公布日期
2012.03.29
申请号
AU20100290931
申请日期
2010.08.23
申请人
PFIZER VACCINES LLC
发明人
CHAMPION, BRIAN ROBERT;CONTILLO JR., LEONARD GABRIEL;EISENBRAUN, MICHAEL DALE;FRASER, JAMES DOWNEY;HAWKINS, JULIE JIA LI;MERSON, JAMES RICHARD;PIERCE, BRIAN GREGORY;QIU, XIAYANG;ULLAH, JAKIR HUSSAIN;WYATT, DAVID MICHAEL