摘要 |
Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.
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申请人 |
ARNOLD LEE D.;COATE HEATHER;CREW ANDREW PHILIP;DONG HANQING;FOREMAN KENNETH;HONDA AYAKO;LAUFER RADOSLAW;LI AN-HU;MULVIHILL KRISTEN MICHELLE;MULVIHILL MARK JOSEPH;NIGRO ANTHONY;PANICKER BIJOY;STEINIG ARNO G.;WENG QINGUA;WERNER DOUGLAS S.;WYLE MICHAEL J.;ZHANG TAO;CESARIO CARA;SUN YINGCHUAN;OSI PHARMACEUTICALS, LLC |
发明人 |
ARNOLD LEE D.;COATE HEATHER;CREW ANDREW PHILIP;DONG HANQING;FOREMAN KENNETH;HONDA AYAKO;LAUFER RADOSLAW;LI AN-HU;MULVIHILL KRISTEN MICHELLE;MULVIHILL MARK JOSEPH;NIGRO ANTHONY;PANICKER BIJOY;STEINIG ARNO G.;WENG QINGUA;WERNER DOUGLAS S.;WYLE MICHAEL J.;ZHANG TAO;CESARIO CARA;SUN YINGCHUAN |