COMPOSITION AND USES THEREOF

摘要

The present invention relates generally to pharmaceutical compositions and their use for the prophylaxis or treatment of conditions associated with hyperglycemia or hypertriglyceridemia, including (but not limited to), diabetes (e.g., Type 2 diabetes) and obesity. The present invention also relates to methods of prophylaxis or treatment of such conditions, based on the finding that an inhibitor of a phosphodiesterase 3 activity and an inhibitor of angiotensin receptor activity provide a desirable synergistic effect on hyperglycemia and hypertriglyceridemia.