发明名称 |
PHARMACEUTICAL SYSTEM FOR TRANS-MEMBRANE DELIVERY. |
摘要 |
<p>Non-invasive drug delivery systems useful for the absorption of therapeutically active agents through the epithelial membrane are described. The non-invasive drug delivery system delivers a therapeutic active agent with an ionizable, or ionized, metal, transition metal or metal-containing vehicle. The non-invasive drug delivery system may also have a pH adjustable vehicle which facilitates the absorption of the therapeutic agents by altering the pH of the non-invasive drug delivery system at the site of administration. Also disclosed is a method for the pH "sweeping" of the administered therapeutic active agent to provide a consistent and reproducible absorption of the active agent. Certain formulations utilize low doses of active agents without altering the active agents from their current or previous form.</p> |
申请公布号 |
MX2011012043(A) |
申请公布日期 |
2012.03.29 |
申请号 |
MX20110012043 |
申请日期 |
2010.05.12 |
申请人 |
PROTEIN DELIVERY SOLUTIONS, LLC.* |
发明人 |
CARVER, DAVID R.;FOHRMAN, TROY;REYNOLDS, SEAN WILLIAM |
分类号 |
A61K9/28 |
主分类号 |
A61K9/28 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|