发明名称 |
MATRIX METALLOPROTEINASE INHIBITORS |
摘要 |
<p>The present invention relates to methyl sulfonamides and N-formamides derivatives of formula (I) and to processes for their syntheses. The invention also relates to pharmacological compositions containing these derivatives and methods of treating asthma, rheumatoid arthritis, COPD, rhinitis, osteoarthritis, psoriatie arthritis, psoriasis, pulmonary fibrosis, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, dry eye, neointimal proliferation which leads to restenosis and ischemic heart failure, stroke, renal disease, tumor metastasis, and other inflammatory disorders characterized by over expression and over activation of an matrix metalloproteinase using the compounds.</p> |
申请公布号 |
CA2812362(A1) |
申请公布日期 |
2012.03.29 |
申请号 |
CA20112812362 |
申请日期 |
2011.09.26 |
申请人 |
RANBAXY LABORATORIES LIMITED |
发明人 |
KHERA, MANOJ KUMAR;PALLE, VENKATA P.;SATTIGERI, VISWAJANANI;SATTIGERI, JITENDRA;SONI, AJAY;RAUF, ABDUL REHMAN ABDUL;SIVAKUMAR, R.;REDDY, RANADHEER R.;MUSIB, ARPITA;CLIFFE, IAN A.;BHATNAGAR, PRADIP KUMAR;RAY, ABHIJIT;SRIVASTAVA, PUNIT;DASTIDAR, SUNANDA GHOSH |
分类号 |
C07D209/48;A61K31/27;A61K31/4035;A61K31/53;A61P11/00;A61P19/02;A61P35/00;C07C271/28;C07D253/04;C07D401/12 |
主分类号 |
C07D209/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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