发明名称 |
Fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives and methods of use thereof |
摘要 |
The present invention relates to novel fluoro-substituted 3,5-dicyano-4-(1-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. |
申请公布号 |
AU2010305550(A1) |
申请公布日期 |
2012.03.29 |
申请号 |
AU20100305550 |
申请日期 |
2010.10.01 |
申请人 |
BAYER PHARMA AKTIENGESELLSCHAFT |
发明人 |
MICHELS, MARTIN;FOLLMANN, MARKUS;VAKALOPOULOS, ALEXANDROS;ZIMMERMANN, KATJA;TEUSCH, NICOLE;LOBELL, MARIO;BIERER, DONALD;ENGEL, KAREN;KISSEL, MARIA |
分类号 |
C07D401/04;A61K31/416 |
主分类号 |
C07D401/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|