| 发明名称 |
STABILIZED COMPOSITIONS FOR RECOMBINANTLY PRODUCED FACTOR VIII |
| 摘要 |
<p>A histidine-free composition comprising: a high purity factor VIII (r-factor VIII); arginine and/or sucrose; a surface-active agent to prevent or at least inhibit surface adsorption of factor VIII; an amount of calcium chloride for specific stabilization of factor VIII.</p> |
| 申请公布号 |
EP2337580(B1) |
申请公布日期 |
2012.03.28 |
| 申请号 |
EP20090782562 |
申请日期 |
2009.09.03 |
| 申请人 |
OCTAPHARMA AG |
发明人 |
RIPPNER, BRITA;OESTERBERG, JOSEFIN;NILSSON, ULRIKA;IVARSSON, ELSA;AGERKVIST, IRENE |
| 分类号 |
A61K9/19;A61K31/195;A61K38/37 |
主分类号 |
A61K9/19 |
| 代理机构 |
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代理人 |
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