发明名称 |
CT/MRI dual-modality molecular imaging contrast agent and method for manufacturing the same |
摘要 |
The present invention relates to a CT/MRI dual modality molecular imaging contrast agent and a method for manufacturing the same. In the present invention, the CT/MRI dual modality molecular imaging contrast agent comprises: an FePt nanoparticle; and a surface modification molecular binding to a surface of the FePt nanoparticle to modify the FePt nanoparticle with an amino-group, a carboxyl-group, or a biotin, wherein the FePt nanoparticle is in a form of sphere, octapod, cuboctahedron, cube, or truncated cube, and the FePt nanoparticle is represented by the following formula (I):
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ Fe x Pt 100-x €ƒ€ƒ€ƒ€ƒ€ƒ(I)
wherein, x is 30ˆ¼60. |
申请公布号 |
EP2433726(A1) |
申请公布日期 |
2012.03.28 |
申请号 |
EP20110250814 |
申请日期 |
2011.09.20 |
申请人 |
NATIONAL CHENG KUNG UNIVERSITY;NATIONAL TAIWAN NORMAL UNIVERSITY |
发明人 |
SHIEH, DAR-BIN;CHEN, CHIA-CHUN;CHOU, SHANG-WEI;WU, PING-CHING;HSIAO, YU-HONG;YANG, YU-SANG |
分类号 |
B22F1/00;A61K49/00;A61K49/04;A61K49/18;B22F9/24 |
主分类号 |
B22F1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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