发明名称 |
Selective reduction and derivatization of engineered proteins comprinsing at least one non-native cysteine |
摘要 |
The present invention relates to method for selective reduction and derivatization of recombinantly prepared engineered proteins comprising at least one non-native cysteine, wherein the reduction reaction is conducted in the presence of a redox buffer or in the presence of a triarylphosphine reducing agent. |
申请公布号 |
EP2360170(A3) |
申请公布日期 |
2012.03.28 |
申请号 |
EP20100196691 |
申请日期 |
2006.06.19 |
申请人 |
NOVO NORDISK HEALTH CARE AG |
发明人 |
OESTERGAARD, HENRIK;PETERSEN, ANDERS, KLARSKOV |
分类号 |
C07K1/113;C07K14/745;C12N9/64 |
主分类号 |
C07K1/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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