COMPOSITION FOR DIAGNOSING CLONORCHIASIS

摘要

PURPOSE: An antigenic protein for the serological diagnosis of clonorchosis and a composition for diagnosis clonorchiosis containing thereof are provided to increase accuracy of diagnosis through the amynologic method. CONSTITUTION: A composition for clonorchiosis diagnosis includes a polypeptide consisting of amino acid sequence of sequence number 8[SEQ ID NO:8](venom3) as an active ingredient. A composition for clonorchiosis diagnosis includes a gene which codes the protein of the sequence number 8 as an active ingredient. The gene coding the protein of the sequence number 8 has DNA sequence of sequence number 16(venom3). The clonorchiosis diagnosis reagent which detects clonorchiosis specific IgG within the blood comprises clonorchiosis imago, metacercaria, or antigen of helminth egg. A clonorchiosis diagnosis reagent includes substrate solution containing anti-human IgG antibody coated fixture, a marker antigen conjugate, and a color fixing agent. The anti-human IgG antibody used for the clonorchiosis diagnosis reagent is chlorine originated anti-human IgG antibody. The antigen of the marker antigen conjugate used for the clonorchiosis diagnosis reagent is clonorchiosis imago, metacercaria, or antigen of helminth egg.