| 发明名称 |
N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-D]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-D]PYRIMIDINES AS JANUS KINASE INHIBITORS |
| 摘要 |
<p>The present invention relates to N-(hetero)aryl-pyrrolidine derivatives of Formula I: which are JAK inhibitors, such as selective JAK1 inhibitors, useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer.</p> |
| 申请公布号 |
EP2432555(A1) |
申请公布日期 |
2012.03.28 |
| 申请号 |
EP20100720113 |
申请日期 |
2010.05.21 |
| 申请人 |
INCYTE CORPORATION |
发明人 |
RODGERS, JAMES, D.;SHEPARD, STACEY;ARVANITIS, ARGYRIOS, G.;WANG, HAISHENG;STORACE, LOUIS;FOLMER, BEVERLY;SHAO, LIXIN;ZHU, WENYU;GLENN, JOSEPH P. |
| 分类号 |
A61P35/00;A61K31/519;C07D487/04 |
主分类号 |
A61P35/00 |
| 代理机构 |
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