摘要 |
<p>Novel title cpds. of formula: (where R1 = H, acyl R2, R3 = H or together form a dialkylmethylene or cycloalkylidene gp) are prepd. by simultaneous fluroination and chlorination of a 6 alpha-fluoro-21-acyloxy-16 alpha-acyloxy-17 alpha-hydroxy-1,4,9(11)-pregnatriene-3,20-dione or its derivs pref. using mixture of HF and a N-chloroacylamide or N-chloroacylimide.</p> |