| 发明名称 |
Methods of treatment using CTLA-4 antibodies |
| 摘要 |
The present invention provides method of treatment using human sequence antibodies against human CTLA-4 linked to a cytotoxic agent. In particular, methods of treating cancer and autoimmune disease are provided. |
| 申请公布号 |
US8142778(B2) |
申请公布日期 |
2012.03.27 |
| 申请号 |
US20080246791 |
申请日期 |
2008.10.07 |
| 申请人 |
DAVIS THOMAS ANDREW;KELER TIBOR P.;GRAZIANO ROBERT F.;KORMAN ALAN J.;MEDAREX, INC. |
发明人 |
DAVIS THOMAS ANDREW;KELER TIBOR P.;GRAZIANO ROBERT F.;KORMAN ALAN J. |
| 分类号 |
A61K39/39;A61K39/395;A61K;A61K38/00;A61K38/16;A61K39/00;A61K39/02;A61K39/12;A61K39/29;A61P1/16;A61P11/06;A61P15/16;A61P19/02;A61P25/28;A61P29/00;A61P31/00;A61P31/04;A61P31/12;A61P31/14;A61P31/16;A61P31/18;A61P31/20;A61P31/22;A61P33/00;A61P33/02;A61P33/06;A61P35/00;A61P37/02;A61P37/04;A61P39/00;A61P43/00;C07K;C07K14/705;C07K16/28;C07K16/30 |
主分类号 |
A61K39/39 |
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