| 摘要 |
<p>A compound of the formula (I) (values R1, R2, R3, R4, R5, R6, R7, A and X are defined in the description), or their separate stereoisomers, or mixture of stereoisomers and optionally their pharmaceutically acceptable salts and solvates, a pharmaceutical compositions containing them and use thereof as MEK inhibitors for treatment of proliferative diseases.</p> |
| 申请人 |
EXELIXIS, INC. |
发明人 |
AAY, NAING;ANAND, NEEL KUMAR;BOWLES, OWEN JOSEPH;BUSSENIUS, JOERG;COSTANZO, SIMONA;CURTIS, JEFFRY KIMO;DUBENKO, LARISA;JOSHI, ANAGHA ABHIJIT;KENNEDY, ABIGAIL R.;KIM, ANGIE INYOUNG;KOLTUN, ELENA;MANALO, JEAN-CLAIRE LIMUN;PETO, CSABA J.;RICE, KENNETH D.;TSANG, TSZE H.;DEFINA, STEVEN CHARLES;BLAZEY, CHARLES M. |
