发明名称 |
METHODS AND COMPOSITIONS FOR TARGETING HETEROLOGOUS INTEGRAL MEMBRANE PROTEINS TO THE CYANOBACTERIAL PLASMA MEMBRANE |
摘要 |
This disclosure pertains to the functional localization of heterologous integral plasma membrane proteins (HIPMPs) lacking cleavable signal sequences into the plasma membrane (PM) of cyanobacterial hosts, e.g., JCC138 (Synechococcus sp. PCC 7002) or an engineered derivative thereof. More specifically, the disclosure provides chimeric integral plasma membrane proteins comprising pseudo leader sequences (PLSs) that promote increased hydrocarbon (e.g., alkane) export capabilities when expressed in a photosynthetic organism, e.g., a cyanobacterium. |
申请公布号 |
WO2012037285(A2) |
申请公布日期 |
2012.03.22 |
申请号 |
WO2011US51643 |
申请日期 |
2011.09.14 |
申请人 |
JOULE UNLIMITED TECHNOLOGIES, INC.;REPPAS, NIKOS, BASIL |
发明人 |
REPPAS, NIKOS, BASIL |
分类号 |
C12N1/21;C07K19/00;C12N1/00;C12N1/11;C12N1/13;C12N1/15;C12N1/19 |
主分类号 |
C12N1/21 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|