发明名称 Apparatus and Method for Reducing the Occurrence of Post-Surgical Adhesions
摘要 A method for inhibiting formation of adhesions following abdominal surgery which involves application of an anti-static fatty acid ethoxylated amide (Cocamide DEA) in a matrix that is placed in the peritoneal cavity at the conclusion of an abdominal surgery and which releases this anti-adhesive chemical over a predetermined time in a range up to seven days. Tests conducted on laboratory rats established that the method reduced the incidence of adhesions from 100 percent (100%) in a test model to near zero in the majority of treated animals. In an alternative embodiment, andrographalide was delivered via a pump with similar results. In still another embodiment, an effective amount of 50% phosphatidylchorene and propylene glycol was delivered, via a pump, into the abdominal cavity, again with similar results.
申请公布号 US2012070473(A1) 申请公布日期 2012.03.22
申请号 US201113302563 申请日期 2011.11.22
申请人 DELANEY JOHN P.;ANHESE LLC 发明人 DELANEY JOHN P.
分类号 A61K9/00;A61K31/164;A61K31/365;A61K31/685;A61P43/00;B82Y5/00 主分类号 A61K9/00
代理机构 代理人
主权项
地址