发明名称 |
TRANSLATION CONSTRUCTION AND ACTIVE SPECIES SEARCH METHOD OF SPECIAL PEPTIDE COMPOUND LIBRARY CONTAINING N-METHYL AMINO ACID AND OTHER SPECIAL AMINO ACIDS |
摘要 |
<P>PROBLEM TO BE SOLVED: To construct a special peptide library using a cell-free (in vitro) translation system and to establish a technology for screening special peptide to be coupled to target protein. <P>SOLUTION: In a method for screening the special peptide compound to be coupled to a target substance from a peptide library, (i) the special peptide library in which the special amino acid is introduced to a peptide sequence at random is prepared by the cell-free translation system containing tRNA made into acyl by the special amino acid, (ii) the obtained special peptide library is brought into contact with the target substance; and (iii) the special peptide to be coupled to the target substance is selected as active peptide. <P>COPYRIGHT: (C)2012,JPO&INPIT |
申请公布号 |
JP2012058092(A) |
申请公布日期 |
2012.03.22 |
申请号 |
JP20100202012 |
申请日期 |
2010.09.09 |
申请人 |
UNIV OF TOKYO |
发明人 |
SUGA HIROAKI;YAMAGISHI YUSUKE |
分类号 |
G01N33/50;C07K7/08;C07K14/00;C12N15/09;C12P21/02;C12Q1/68;C40B40/08;C40B40/10;G01N33/566 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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