METHOD OF PREPARATION OF HIGHLY SUBSTITUTED HYALURONIC ACID AMIDES
摘要
The invention relates to the method of preparation of highly substituted hyaluronic acid amides with a controllable degree of substitution, which are prepared in a polar aprotic environment from an acidic form of hyaluronic acid in the presence of ethylchloroformiate, by means of a primary amine.
申请公布号
WO2012034544(A2)
申请公布日期
2012.03.22
申请号
WO2011CZ00089
申请日期
2011.09.08
申请人
CONTIPRO BIOTECH S R.O.;HUERTA-ANGELES, GLORIA;CHLADKOVA, DRAHOMIRA;SMEJKALOVA, DANIELA;BUFFA, RADOVAN;VELEBNY, VLADIMIR
发明人
HUERTA-ANGELES, GLORIA;CHLADKOVA, DRAHOMIRA;SMEJKALOVA, DANIELA;BUFFA, RADOVAN;VELEBNY, VLADIMIR