摘要 |
<P>PROBLEM TO BE SOLVED: To provide a novel compound to quickly modify RNA in a specific sequence and in a specific site. <P>SOLUTION: The compound is shown by general formula II. In the formula, R<SP POS="POST">1</SP>is H, C<SB POS="POST">1-6</SB>alkyl or C<SB POS="POST">1-6</SB>aryl; and X is Br, Cl or I. The compound shown by the formula, and an oligonucleotide containing 6-thio guanosine are made to react to produce a functional group transition nucleic acid, the obtained functional group transition nucleic acid and RNA are made to react to produce RNA into which a functional molecule has been introduced. <P>COPYRIGHT: (C)2012,JPO&INPIT |