发明名称 QUICK RNA MODIFICATION METHOD USING FUNCTIONAL GROUP TRANSITION NUCLEIC ACID
摘要 <P>PROBLEM TO BE SOLVED: To provide a novel compound to quickly modify RNA in a specific sequence and in a specific site. <P>SOLUTION: The compound is shown by general formula II. In the formula, R<SP POS="POST">1</SP>is H, C<SB POS="POST">1-6</SB>alkyl or C<SB POS="POST">1-6</SB>aryl; and X is Br, Cl or I. The compound shown by the formula, and an oligonucleotide containing 6-thio guanosine are made to react to produce a functional group transition nucleic acid, the obtained functional group transition nucleic acid and RNA are made to react to produce RNA into which a functional molecule has been introduced. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012056895(A) 申请公布日期 2012.03.22
申请号 JP20100202349 申请日期 2010.09.09
申请人 KYUSHU UNIV 发明人 SASAKI SHIGEKI;ONIZUKA KAZUMITSU;TANIGUCHI YOSUKE
分类号 C07H21/02;C07C49/80;C07C247/04;C07D495/04;C12N15/00 主分类号 C07H21/02
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