发明名称 |
POLYPEPTIDE HAVING D-LACTATE DEHYDROGENASE ACTIVITY, POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE, AND PROCESS FOR PRODUCTION OF D-LACTIC ACID |
摘要 |
Highly productive D-lactic acid fermentation uses a transformant obtained by introducing into a host cell a polynucleotide encoding a polypeptide according to any one of the following (A) to (C) in such a manner that the polypeptide is expressed, which polypeptide has a D-lactate dehydrogenase activity higher than those of conventional polypeptides: (A) a polypeptide having the amino acid sequence shown in SEQ ID NO:1 or 2; (B) a polypeptide having the same amino acid sequence as shown in SEQ ID NO:1 or 2 except that one or several amino acids are substituted, deleted, inserted and/or added, which polypeptide has a D-lactate dehydrogenase activity; and (C) a polypeptide having an amino acid sequence which has a sequence identity of not less than 80% to the amino acid sequence shown in SEQ ID NO:1 or 2, which polypeptide has a D-lactate dehydrogenase activity. |
申请公布号 |
US2012070871(A1) |
申请公布日期 |
2012.03.22 |
申请号 |
US201013375882 |
申请日期 |
2010.06.02 |
申请人 |
SAWAI KENJI;SUDA KAZUMI;SAWAI HIDEKI;YAMADA KATSUSHIGE;YAMAGISHI JUNYA;TORAY INDUSTRIES, INC. |
发明人 |
SAWAI KENJI;SUDA KAZUMI;SAWAI HIDEKI;YAMADA KATSUSHIGE;YAMAGISHI JUNYA |
分类号 |
C12P7/56;C12N1/19;C12N9/04;C12N15/53;C12N15/63 |
主分类号 |
C12P7/56 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|