发明名称 |
Methods And Marker Combinations For Screening For Predisposition To Lung Cancer |
摘要 |
The present invention relates to rapid, sensitive methods for determining whether a subject has or is at risk of developing lung cancer based on certain combinations of biomarkers, or biomarkers and biometric parameters. The methods consist of: a) quantifying in a test sample obtained from a subject, the amount of two or more biomarkers in a panel, the panel comprising at least one antibody and at least one antigen: b) comparing the amount of each biomarker quantified in the panel to a predetermined cutoff for said biomarker and assigning a score for each biomarker based on said comparison: c) combining the assigned score for each biomarker quantified in step b to obtain a total score for said subject: d) comparing the total score in step c with a predetermined total score and e) determining whether said subject has a risk of lung cancer based on the comparison in step d.
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申请公布号 |
US2012071334(A1) |
申请公布日期 |
2012.03.22 |
申请号 |
US20080667069 |
申请日期 |
2008.06.27 |
申请人 |
COLPITTS TRACEY;RUSSELL ERIC L.;FROST STEPHEN;RAMIREZ JAVIER;SINGH BHAWANI;RUSSELL JOHN C.;ABBOTT LABORATORIES |
发明人 |
COLPITTS TRACEY;RUSSELL ERIC L.;FROST STEPHEN;RAMIREZ JAVIER;SINGH BHAWANI;RUSSELL JOHN C. |
分类号 |
C40B30/04;C07K7/08;C07K14/435;G01N33/53;G01N33/566 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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