发明名称 |
Modulation of diacylglycerol acyltransferase 1 expression |
摘要 |
<p>Compounds, compositions and methods are provided for modulating the expression of diacylglycerol acyltransferase 1. The compositions comprise oligonucleotides, targeted to nucleic acid encoding diacylglycerol acyltransferase 1. Methods of using these compounds for modulation of diacylglycerol acyltransferase 1 expression and for diagnosis and treatment of disease associated with expression of diacylglycerol acyltransferase 1, such as obesity and obesity-related conditions, are provided.</p> |
申请公布号 |
EP2281869(A3) |
申请公布日期 |
2012.03.21 |
申请号 |
EP20100177263 |
申请日期 |
2004.03.19 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MONIA, BRETT, P.;GRAHAM, MARK, J. |
分类号 |
C12N1/00;A61K38/00;C12N9/10;C12N15/113 |
主分类号 |
C12N1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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