发明名称 (2S,3R)-N-(2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide, novel salt forms, and methods of use thereof
摘要 The present invention provides a compound (2S,3R) N-(2-((3-pyridinyl)methyl-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide or a pharmaceutically acceptable salt thereof, and which is substantially free of (2S,3S) N-(2-((3-pyridinyl)methyl-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide or a pharmaceutically acceptable salt thereof, (2R,3S) N-(2-((3-pyridinyl)methyl-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide or a pharmaceutically acceptable salt thereof, or (2R,3R) N-(2-((3-pyridinyl)methyl-1-azabicyclo[2.2.2]oct-3-yl)benzofuran-2-carboxamide or a pharmaceutically acceptable salt thereof.
申请公布号 EP2431037(A1) 申请公布日期 2012.03.21
申请号 EP20110194142 申请日期 2008.08.01
申请人 TARGACEPT, INC. 发明人 MAZUROV, ANATOLY A.;PHILLIPS, TERESA Y.
分类号 A61K31/4545;A61K45/06;A61P3/00;A61P3/10;A61P25/00;A61P43/00;C07D453/02 主分类号 A61K31/4545
代理机构 代理人
主权项
地址