发明名称 |
METHODS FOR THE COLLECTION AND MATURATION OF OOCYTES |
摘要 |
<p>The present invention relates to a method of producing an embryo from an oocyte by an assisted reproduction technology. The method includes (a) collecting an oocyte from an ovary of a subject in a collection medium comprising a first phosphodiesterase inhibitor and an agent that increases intracellular cAMP concentration in the oocyte, (b) culturing the oocyte in a maturation medium comprising a second phosphodiesterase inhibitor, and (c) producing an embryo from the oocyte by an assisted reproduction technology. The present invention also relates to methods of inducing oocyte maturation. For example a method of in vitro maturation of an oocyte is described which comprises steps (a) and (b) above. The present invention also relates to an oocyte maturation medium comprising a phosphodiesterase inhibitor and a ligand for inducing maturation of the oocyte. A combination product comprising an oocyte collection and maturation medium referred to above is also described.</p> |
申请公布号 |
EP2430154(A1) |
申请公布日期 |
2012.03.21 |
申请号 |
EP20100774437 |
申请日期 |
2010.05.14 |
申请人 |
ADELAIDE RESEARCH & INNOVATION PTY LTD. |
发明人 |
GILCHRIST, ROBERT, BRUCE;THOMPSON, JEREMY;ALBUZ, FIRAS |
分类号 |
C12N5/075;C12N5/02 |
主分类号 |
C12N5/075 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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