3-(4-AMINOPHENYL)-2-FURANCARBOXYLIC ACID DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

摘要

Disclosed is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof:
wherein R 1 is
1: a C 3-8 cycloalkyl C 1-4 alkyl group,
2: a C 7-14 aralkyl group, in which the aryl moiety thereof is optionally substituted with the same or different 1 to 3 groups selected from the group consisting of:
(a) halogen,
(b) C 1-4 alkyl, which is optionally substituted with 1 to 3 fluorine atoms,
(c) C 1-4 alkoxy, which is optionally substituted with 1 to 3 fluorine atoms, and
(d) C 1-4 alkylcarbonyl, which is optionally substituted with C 1-4 alkoxy,
3: a five- to ten-membered heteroaryl-C 1-4 alkyl group, in which the heteroaryl moiety thereof is optionally substituted with the same or different 1 to 3 groups selected from the group consisting of:
(a) halogen, and
(b) C 1-4 alkyl, or
4: a C 6-10 aryl C 2-6 alkenyl group; and
R 2 is a cyano group or a nitro group.