摘要 |
<p>The present invention provides compounds that are PIKK inhibitors, more specifically, mTOR and/or PI3Kα kinase inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of kinases, specifically PI3 kinases, more specifically, mTOR and/or PI3Kα, such as cancer. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.</p> |
申请人 |
AMGEN, INC |
发明人 |
BODE, CHRISTIANE;BOEZIO, ALESSANDRO;CHENG, ALAN, C.;CHOQUETTE, DEBORAH;COATS, JAMES, R.;COPELAND, KATRINA, W.;HUANG, HONGBING;LA, DANIEL;LEWIS, RICHARD;LIAO, HONGYU;POTASHMAN, MICHELE;STELLWAGEN, JOHN;YI, SHUYAN;NORMAN, MARK;STEC, MARKIAN;PETERSON, EMILY, A.;GRACEFFA, RUSSELL |