发明名称 HETEROARYL COMPOUNDS AS PIKK INHIBITORS
摘要 <p>The present invention provides compounds that are PIKK inhibitors, more specifically, mTOR and/or PI3K&alpha; kinase inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of kinases, specifically PI3 kinases, more specifically, mTOR and/or PI3K&alpha;, such as cancer. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.</p>
申请公布号 EP2430013(A1) 申请公布日期 2012.03.21
申请号 EP20100719514 申请日期 2010.05.12
申请人 AMGEN, INC 发明人 BODE, CHRISTIANE;BOEZIO, ALESSANDRO;CHENG, ALAN, C.;CHOQUETTE, DEBORAH;COATS, JAMES, R.;COPELAND, KATRINA, W.;HUANG, HONGBING;LA, DANIEL;LEWIS, RICHARD;LIAO, HONGYU;POTASHMAN, MICHELE;STELLWAGEN, JOHN;YI, SHUYAN;NORMAN, MARK;STEC, MARKIAN;PETERSON, EMILY, A.;GRACEFFA, RUSSELL
分类号 C07D401/14;A61K31/437;A61K31/506;A61K31/52;A61K31/53;A61P35/00;C07D403/04;C07D403/14;C07D471/04;C07D487/04;C07D519/00 主分类号 C07D401/14
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