发明名称 |
Membrane active heteropolymers |
摘要 |
The present invention is directed to a class of membrane active polymers useful for cellular delivery of compounds. Conjugation of the described membrane active polymers to targeting, anti-opsonization, and anti-aggregation agents provides polymers suitable for in vivo delivery. The use of multiple reversible linkages connecting component parts provides for physiologically responsive activity modulation. |
申请公布号 |
US8138383(B2) |
申请公布日期 |
2012.03.20 |
申请号 |
US20080123104 |
申请日期 |
2008.05.19 |
申请人 |
WAKEFIELD DARREN H.;ROZEMA DAVID B.;WOLFF JON A.;HAGSTROM JAMES E.;ARROWHEAD MADISON INC. |
发明人 |
WAKEFIELD DARREN H.;ROZEMA DAVID B.;WOLFF JON A.;HAGSTROM JAMES E. |
分类号 |
C07C9/22 |
主分类号 |
C07C9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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