| 发明名称 |
AGGRECANASE-1 AND -2 PEPTIDE SUBSTRATES AND METHODS |
| 摘要 |
The present invention describes synthetic peptide substrates of the metalloproteases, agggrecanase-1 and/or -2 suitable for assays of enzyme activity. The invention also describes methods using these peptides to discover pharmaceutical agents that modulate these proteases.
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| 申请公布号 |
CA2473513(C) |
申请公布日期 |
2012.03.20 |
| 申请号 |
CA20032473513 |
申请日期 |
2003.01.15 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
FOURIE, ANNE;KARLSSON, LARS;COLES, FAWN |
| 分类号 |
C12N9/50;A61K38/00;C07K1/00;C12N9/64;C12N15/09;C12Q1/37;G01N33/573 |
主分类号 |
C12N9/50 |
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